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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Sophora japonica
TCM herb Huai Hua (flower buds/fruits); rich in rutin for capillary protection and hemorrhoid treatment.
Sophora japonica (Huai Hua) is a traditional Chinese medicinal herb whose flower buds and fruits are rich in rutin, a flavonoid glycoside with potent capillary-protective and antihemorrhagic properties. It is primarily used for hemorrhoids, varicose veins, and capillary fragility, and also exhibits anti-inflammatory and hemostatic effects due to its content of quercetin, sophocarpine, matrine, and sophoridine. Evidence is limited to small clinical studies and traditional use, placing it at evidence level C.
Rutin and quercetin inhibit hyaluronidase and collagenase, strengthening capillary walls and reducing permeability. They also inhibit platelet aggregation and exert antioxidant effects via scavenging reactive oxygen species. The alkaloids matrine and sophoridine modulate inflammatory pathways by suppressing NF-κB activation and reducing TNF-α, IL-6, and COX-2 expression. Additionally, sophocarpine has been shown to activate the arachidonic acid cascade, promoting hemostasis through thromboxane A2 synthesis. These combined actions support the herb's use in hemorrhoidal conditions and microvascular fragility.
TCM herb Huai Hua (flower buds/fruits); rich in rutin for capillary protection and hemorrhoid treatment.
Sophora japonica (Huai Hua) is a traditional Chinese medicinal herb whose flower buds and fruits are rich in rutin, a flavonoid glycoside with potent capillary-protective and antihemorrhagic properties. It is primarily used for hemorrhoids, varicose veins, and capillary fragility, and also exhibits anti-inflammatory and hemostatic effects due to its content of quercetin, sophocarpine, matrine, and sophoridine. Evidence is limited to small clinical studies and traditional use, placing it at evidence level C.
Rutin and quercetin inhibit hyaluronidase and collagenase, strengthening capillary walls and reducing permeability. They also inhibit platelet aggregation and exert antioxidant effects via scavenging reactive oxygen species. The alkaloids matrine and sophoridine modulate inflammatory pathways by suppressing NF-κB activation and reducing TNF-α, IL-6, and COX-2 expression. Additionally, sophocarpine has been shown to activate the arachidonic acid cascade, promoting hemostasis through thromboxane A2 synthesis. These combined actions support the herb's use in hemorrhoidal conditions and microvascular fragility.