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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Sophora tetraptera
New Zealand's national flower, a tree used by Maori for skin conditions and wounds with the flowers and bark having medicinal properties despite toxicity concerns.
Sophora tetraptera, the New Zealand kōwhai, is a tree whose bark and flowers have traditional Māori uses for skin conditions and wounds, though its quinolizidine alkaloids (cytisine, matrine, baptifoline) confer significant toxicity. Modern research focuses on topical wound healing and hair growth, but internal use is contraindicated due to risk of severe alkaloid poisoning.
The primary alkaloids, particularly cytisine, act as partial agonists at nicotinic acetylcholine receptors (nAChRs), which may stimulate hair follicle activity and modulate inflammation. Matrine exhibits anti-inflammatory and antimicrobial effects via inhibition of NF-κB and bacterial cell wall synthesis. Baptifoline contributes to neuromuscular blockade at high doses, explaining the paralysis seen in toxicity. Topical application likely limits systemic absorption, but even percutaneous uptake can cause adverse effects.
New Zealand's national flower, a tree used by Maori for skin conditions and wounds with the flowers and bark having medicinal properties despite toxicity concerns.
Sophora tetraptera, the New Zealand kōwhai, is a tree whose bark and flowers have traditional Māori uses for skin conditions and wounds, though its quinolizidine alkaloids (cytisine, matrine, baptifoline) confer significant toxicity. Modern research focuses on topical wound healing and hair growth, but internal use is contraindicated due to risk of severe alkaloid poisoning.
The primary alkaloids, particularly cytisine, act as partial agonists at nicotinic acetylcholine receptors (nAChRs), which may stimulate hair follicle activity and modulate inflammation. Matrine exhibits anti-inflammatory and antimicrobial effects via inhibition of NF-κB and bacterial cell wall synthesis. Baptifoline contributes to neuromuscular blockade at high doses, explaining the paralysis seen in toxicity. Topical application likely limits systemic absorption, but even percutaneous uptake can cause adverse effects.