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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Trichosanthes kirilowii
TCM herb used to clear heat and generate fluid; used for thirst, lung heat cough, breast conditions, and historically for abortion (unsafe, professional only).
Tian Hua Fen, the root of Trichosanthes kirilowii, is a traditional Chinese medicine used to clear heat, generate fluids, and treat thirst, lung heat cough, and breast conditions. Its primary active compound, trichosanthin, exhibits abortifacient and immunomodulatory properties, while polysaccharides and cucurbitacins contribute to hypoglycemic and anti-inflammatory effects. Modern research supports its use in diabetes support and antiviral applications, though clinical evidence remains limited.
Trichosanthin, a type I ribosome-inactivating protein, inhibits protein synthesis by depurinating adenine residues in 28S rRNA, leading to cell death and immune modulation. It also activates MAPK pathways and induces apoptosis in certain cancer cells. The polysaccharides enhance glucose uptake via AMPK activation, while cucurbitacins inhibit STAT3 signaling, contributing to anti-inflammatory effects. These mechanisms collectively support its traditional uses in heat conditions and modern applications in diabetes and inflammation.
TCM herb used to clear heat and generate fluid; used for thirst, lung heat cough, breast conditions, and historically for abortion (unsafe, professional only).
Tian Hua Fen, the root of Trichosanthes kirilowii, is a traditional Chinese medicine used to clear heat, generate fluids, and treat thirst, lung heat cough, and breast conditions. Its primary active compound, trichosanthin, exhibits abortifacient and immunomodulatory properties, while polysaccharides and cucurbitacins contribute to hypoglycemic and anti-inflammatory effects. Modern research supports its use in diabetes support and antiviral applications, though clinical evidence remains limited.
Trichosanthin, a type I ribosome-inactivating protein, inhibits protein synthesis by depurinating adenine residues in 28S rRNA, leading to cell death and immune modulation. It also activates MAPK pathways and induces apoptosis in certain cancer cells. The polysaccharides enhance glucose uptake via AMPK activation, while cucurbitacins inhibit STAT3 signaling, contributing to anti-inflammatory effects. These mechanisms collectively support its traditional uses in heat conditions and modern applications in diabetes and inflammation.