Loading...
Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
Loading...
Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Tinospora crispa
Climbing vine native to Southeast Asia used in traditional medicine of Malaysia, Thailand, Indonesia, and the Philippines for diabetes, malaria, and fever.
Tinospora crispa is a climbing vine native to Southeast Asia, traditionally used for diabetes, malaria, and fever. Modern research indicates antidiabetic, antiplasmodial, antipyretic, and anti-inflammatory activities, attributed to compounds such as borapetoside, tinoscorbiside, berberine, and picrotoxin. Evidence level C suggests limited clinical data supporting these uses.
The antidiabetic effect is primarily mediated by berberine, which activates AMP-activated protein kinase (AMPK), enhancing insulin sensitivity and glucose uptake. Antiplasmodial activity involves inhibition of Plasmodium falciparum growth via disruption of heme detoxification and possibly through alkaloid-induced oxidative stress. Antipyretic and anti-inflammatory actions are linked to suppression of prostaglandin synthesis and modulation of cytokine release, while picrotoxin-like compounds may contribute to CNS effects by antagonizing GABA-A receptors.
Climbing vine native to Southeast Asia used in traditional medicine of Malaysia, Thailand, Indonesia, and the Philippines for diabetes, malaria, and fever.
Tinospora crispa is a climbing vine native to Southeast Asia, traditionally used for diabetes, malaria, and fever. Modern research indicates antidiabetic, antiplasmodial, antipyretic, and anti-inflammatory activities, attributed to compounds such as borapetoside, tinoscorbiside, berberine, and picrotoxin. Evidence level C suggests limited clinical data supporting these uses.
The antidiabetic effect is primarily mediated by berberine, which activates AMP-activated protein kinase (AMPK), enhancing insulin sensitivity and glucose uptake. Antiplasmodial activity involves inhibition of Plasmodium falciparum growth via disruption of heme detoxification and possibly through alkaloid-induced oxidative stress. Antipyretic and anti-inflammatory actions are linked to suppression of prostaglandin synthesis and modulation of cytokine release, while picrotoxin-like compounds may contribute to CNS effects by antagonizing GABA-A receptors.