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PubMed · [Aerobiological study in Lima, Perú. ¿Tipuana-Tipu, perhaps a new allergen?]. (2024)
PubMed · LC-MS/MS profiling of Tipuana tipu flower, HPLC-DAD quantification of its bioactive components, and interrelationships with antioxidant, and anti-inflammatory activity: in vitro and in silico approaches. (2024)
Révisé par : HerbAlly Editorial Team, Medical herbalists and healthcare professionals
Cette fiche a été compilée à partir de résumés PubMed (NIH) avec l'assistance d'une IA. Chaque affirmation factuelle est citée par un article PubMed réel (voir la liste des sources). Elle n'a pas encore été révisée par un humain — confirmez auprès d'un professionnel de santé avant utilisation.
Compilé à partir de 30 articles PubMed · modèle : gemma4:31b
Résumé
Tipuana tipu is a leguminous tree indigenous to Argentina and used extensively in urban landscaping [PMID:12710729]. It is studied for its potential antioxidant, anti-inflammatory, and antidiabetic properties [PMID:38671392, PMID:42245235].
Contexte
Tipuana tipu (Benth.) Kuntze is a tree of the Fabaceae family (Papilionoideae) indigenous to Argentina and widely used in urbanism, particularly in Southern Brazil [PMID:12710729, PMID:37312011].
Usages traditionnels
Tipuana tipu is described as a leguminous plant traditionally valued for various medicinal properties [PMID:42245235].
Composés actifs
The flowers contain bioactive components analyzed via LC-MS/MS [PMID:38671392]. Leaf extracts contain flavonoids including kaempferol, quercetin, rutin, and chlorogenic acid [PMID:24144158, PMID:25169776]. Epicuticular waxes of leaves, branches, and flowers contain aliphatic alcohols, alkanes, aliphatic acids, and lupeol and b-amyrin hexadecanoates [PMID:12710729]. Essential oils from different parts of the tree contain sesquiterpene hydrocarbons (e.g., β-caryophyllene, germacrene D) in roots, and non-terpene hydrocarbons (e.g., n-tetradecane, 1,7-dimethylnaphthalene, n-octadecane) in pods, leaves, stems, and flowers [PMID:26916976]. Leaf leachates are characterized by condensed tannins and oxalic acid (cyclohexyl hexyl ester) [PMID:41480725].
Mécanisme d'action
In silico docking suggests that phytocompounds from T. tipu leaves (nonadecanol, alpinumisoflavone, β-sitosterol glucoside, protocatechualdehyde, and protocatechuic acid) may bind with carbohydrate-digesting enzymes α-amylase and α-glucosidase [PMID:42245235]. Methanol extracts of flowers have shown inhibitory activity against iNOS, NO production, and pro-inflammatory cytokines including NF-KB, TNF-R2, TNF-α, IL-1β, and IL-6 in LPS-activated RAW 264.7 macrophages [PMID:38671392].
Preuves cliniques
Preuve DHyperglycemia
Methanolic extract of T. tipu (METT) demonstrated glucose-lowering activity in streptozotocin-induced diabetic rats [PMID:42245235]
Preuve DInflammation
Leaf extracts containing acylated kaempferol glycosides showed anti-inflammatory activity in a carrageenin-induced rat paw oedema model [PMID:25169776]
Preuve DOxidative Stress
Methanol extracts of flowers exhibited antioxidant activity in DPPH, ABTS, and FRAP assays [PMID:38671392]
Sécurité et effets indésirables
Tipuana tipu pollen has been reported as a potential new allergen capable of triggering allergic symptoms [PMID:38683076].
Synthèse des preuves
The current evidence for Tipuana tipu is primarily based on in vitro assays and animal models (Level D), focusing on phytochemical profiling and preliminary pharmacological activities such as antioxidant, anti-inflammatory, and antihyperglycemic effects.
Sources PubMed
1.PMID: 37312011 (2023) — Predatory Arthropods Associated with the Invasive Tipu Psyllid, Platycorypha nigrivirga, in Southern Spain. · Neotropical entomology
2.PMID: 38671392 (2024) — LC-MS/MS profiling of Tipuana tipu flower, HPLC-DAD quantification of its bioactive components, and interrelationships with antioxidant, and anti-inflammatory activity: in vitro and in silico approaches. · BMC complementary medicine and therapies
3.PMID: 38683076 (2024) — [Aerobiological study in Lima, Perú. ¿Tipuana-Tipu, perhaps a new allergen?]. · Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
4.PMID: 42245235 (2026) — Antidiabetic effects of Tipuana tipu leaves: in silico docking and experimental study in streptozotocin-induced diabetic rats. · In silico pharmacology
Aucune monographie gouvernementale directe n'est disponible pour cette plante. Le contenu ci-dessous est généré par IA et n'a pas été vérifié par rapport à une source gouvernementale faisant autorité. Utilisez les liens de recherche pour consulter les sources officielles avant de vous fier à ces informations.
— Chemical composition of Tipuana tipu, a source for tropical honey bee products.
· Zeitschrift fur Naturforschung. C, Journal of biosciences
6.PMID: 26916976 (2016) — Chemical Composition and Allelopathic Potential of Essential Oils from Tipuana tipu (Benth.) Kuntze Cultivated in Tunisia. · Chemistry & biodiversity
7.PMID: 24144158 (2014) — Flavonoids with acetylated branched glycans and bioactivity of Tipuana tipu (Benth.) Kuntze leaf extract. · Natural product research
8.PMID: 25169776 (2015) — A new acylated flavonoid tetraglycoside with anti-inflammatory activity from Tipuana tipu leaves. · Natural product research
9.PMID: 41480725 (2026) — From fertilizer to insecticide: urban leaf litter chemistry alters the survival landscape of Aedes aegypti. · Pest management science