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Ce produit n'est pas destiné à diagnostiquer, traiter, guérir ou prévenir toute maladie. Ces déclarations n'ont pas été évaluées par la Food and Drug Administration.
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Ces informations sont fournies à titre éducatif uniquement et ne remplacent pas un avis médical professionnel, un diagnostic ou un traitement. Consultez toujours votre professionnel de santé avant d'utiliser des plantes, surtout si vous êtes enceinte, allaitez, prenez des médicaments ou avez une condition médicale.
Drimia indica
An Indian relative of Mediterranean squill used in Ayurveda similarly as expectorant and cardiac tonic.
Urginea indica (Indian squill) is a bulbous plant used in Ayurveda primarily as an expectorant and cardiac tonic. Its key active compounds include bufadienolides (e.g., proscillaridin A) and flavonoids, which confer both therapeutic and toxic effects. Due to its narrow therapeutic index and potential for cardiac toxicity, its use is largely restricted to standardized pharmaceutical preparations.
The bufadienolides in Urginea indica (e.g., proscillaridin A) inhibit the Na+/K+-ATPase pump in cardiac myocytes, increasing intracellular calcium and enhancing myocardial contractility (positive inotrope). This mechanism is similar to that of digitalis glycosides. The expectorant action is thought to result from reflex stimulation of gastric mucosa via vagal afferents, leading to increased bronchial secretion. Additionally, the plant's saponins and flavonoids may contribute to mild diuretic and anti-inflammatory effects. However, due to its narrow therapeutic index, the margin between therapeutic and toxic doses is small, and overdose can lead to severe cardiac arrhythmias.
An Indian relative of Mediterranean squill used in Ayurveda similarly as expectorant and cardiac tonic.
Urginea indica (Indian squill) is a bulbous plant used in Ayurveda primarily as an expectorant and cardiac tonic. Its key active compounds include bufadienolides (e.g., proscillaridin A) and flavonoids, which confer both therapeutic and toxic effects. Due to its narrow therapeutic index and potential for cardiac toxicity, its use is largely restricted to standardized pharmaceutical preparations.
The bufadienolides in Urginea indica (e.g., proscillaridin A) inhibit the Na+/K+-ATPase pump in cardiac myocytes, increasing intracellular calcium and enhancing myocardial contractility (positive inotrope). This mechanism is similar to that of digitalis glycosides. The expectorant action is thought to result from reflex stimulation of gastric mucosa via vagal afferents, leading to increased bronchial secretion. Additionally, the plant's saponins and flavonoids may contribute to mild diuretic and anti-inflammatory effects. However, due to its narrow therapeutic index, the margin between therapeutic and toxic doses is small, and overdose can lead to severe cardiac arrhythmias.