PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Topical Alchemilla vulgaris in glycerine was compared to dexamethasone for reducing sore throat and hoarseness after tracheal intubation [PMID:33866772]
An ointment containing A. vulgaris and Mimosa tenuiflora promoted faster wound healing, re-epithelialization, and collagen synthesis in mice compared to fusidic acid [PMID:29966977]
Oral administration of A. vulgaris extract in a DHEA-induced rat model was investigated for effects on ovarian morphology and endocrine biomarkers [PMID:40550985]
A. vulgaris treatment mitigated isoproterenol-induced myocardial damage by enhancing SOD and CAT activities and reducing oxidative stress in mice [PMID:39170697]
Extracts suppressed growth of human tumor cell lines (MCF-7, A375, A549, HCT116) and showed antimelanoma activity in murine models [PMID:36500205, 38920557]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 28744637 (2017) — Antiviral Activity of Lady's Mantle (Alchemilla vulgaris L.) Extracts against Orthopoxviruses. · Bulletin of experimental biology and medicine
- 2.PMID: 37981119 (2024) — A review of the traditional uses, phytochemistry, pharmacology, and clinical evidence for the use of the genus Alchemilla (Rosaceae). · Journal of ethnopharmacology
- 3.PMID: 36500205 (2022) — Beyond Traditional Use of Alchemilla vulgaris: Genoprotective and Antitumor Activity In Vitro. · Molecules (Basel, Switzerland)
- 4.PMID: 38920557 (2024) — Antimelanoma Effects of Alchemilla vulgaris: A Comprehensive In Vitro and In Vivo Study. · Diseases (Basel, Switzerland)
- 5.PMID: 35542286 (2019)