PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Polysaccharides (PAP) effectively reduced inflammatory levels and associated intestinal mucosal barrier impairment in mouse models [PMID:39922353]
Flavonoids (PAF) mitigated weight loss, blood in stool, and diarrhea in DSS-induced colitis mice, while enhancing antioxidant activity [PMID:40636944]
Aqueous extracts and polysaccharides significantly inhibited cough frequency and showed expectorant activity in animal models [PMID:26695537]
Saponins 1-8, 14, and 22 displayed potent hepatoprotective activities, and several others showed anti-inflammatory effects [PMID:34288682]
Phenols improved insulin-stimulated glucose uptake and decreased lipid droplet accumulation in 3T3-L1 adipocytes in vitro [PMID:36717756]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 38855725 (2023) — The genome sequence of the silverweed cinquefoil, Potentilla anserina L., 1753. · Wellcome open research
- 2.PMID: 39922353 (2025) — Potentilla anserina L. polysaccharide ameliorates LPS-induced acute lung injury and relevant intestinal mucosal barrier impairment. · International journal of biological macromolecules
- 3.PMID: 34288682 (2021) — Pentacyclic Triterpenoid Saponins, Poterinasides A-J, from Silverweed Cinquefoil Roots Promising Hepatoprotective and Anti-inflammatory Agents. · The Journal of organic chemistry
- 4.PMID: 34659986 (2021) — Confusion Syndrome During COVID-19: The "Herb" That Hides the Forest? · Cureus
- 5.PMID: 38909825 (2024)