PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 29 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Lupane-type triterpenes (specifically betulone) from the bark showed significant antiparasitic activity in vitro with an IC50 of 2.7 ± 1.2 μM [PMID:35142606].
Aqueous and ethanolic extracts of acorns inhibited the growth of human skin epidermoid carcinoma (A431) and lung carcinoma (A549) cell lines [PMID:35566154].
Acorn extracts inhibited growth of Gram-positive (S. aureus, B. subtilis, S. mutans), Gram-negative (E. coli, C. freundii, P. mirabilis, P. aeruginosa) microorganisms, and yeast-like fungi (C. albicans, C. glabrata) [PMID:35566154].
Evidence summary
PubMed sources
- 1.PMID: 37764031 (2023) — The Good, the Bad, and the Useable Microbes within the Common Alder (Alnus glutinosa) Microbiome-Potential Bio-Agents to Combat Alder Dieback. · Microorganisms
- 2.PMID: 38300340 (2024) — Element contents and their seasonal dynamics in leaves of alder Alnus glutinosa (L.) Gaertn. · Environmental monitoring and assessment
- 3.PMID: 35142606 (2022) — Anti-Toxoplasma gondii effect of lupane-type triterpenes from the bark of black alder (Alnus glutinosa) and identification of a potential target by reverse docking. · Parasite (Paris, France)
- 4.PMID: 35566154 (2022) — Chemical Characteristics of Ethanol and Water Extracts of Black Alder (Alnus glutinosa L.) Acorns and Their Antibacterial, Anti-Fungal and Antitumor Properties. · Molecules (Basel, Switzerland)
- 5.PMID: 41976229