PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 16 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A mixture of kaempferol-3-O-sambubioside and kaempferol-3-O-sophoroside (30-180 mg/kg) significantly prevented ethanol-induced gastric lesions, edema, and microscopic damage in rats [PMID:36365404]
Ethyl acetate and dichloromethane fractions of aerial parts alleviated CCl4-induced liver injury in rats, reducing ALT, AST, ALP, total bilirubin, and MDA levels [PMID:30138328]
Aqueous lyophilisate of leaves demonstrated anticonvulsant effects against pentylenetetrazole (PTZ)-induced seizures [PMID:36509255]
Hexane extracts of stems and leaves showed vasorelaxant activity in ex vivo rat thoracic aorta assays [PMID:33560535]
Ethanol extracts of red flowers showed antibacterial activity (notably against Vibrio damsela) and antifungal activity (notably against Aspergillus terreus) [PMID:36421296]; aqueous leaf extracts were positive against six human pathogenic bacteria [PMID:30917135]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 31390115 (2020) — Metabolomics analysis and biological investigation of three Malvaceae plants. · Phytochemical analysis : PCA
- 2.PMID: 36509255 (2023) — Revealing the most effective anticonvulsant part of Malvaviscus arboreus Dill. Ex Cav. and its acute and sub-acute toxicity. · Journal of ethnopharmacology
- 3.PMID: 33253829 (2021) — Gastroprotective activity of kaempferol glycosides from Malvaviscus arboreus Cav. · Journal of ethnopharmacology
- 4.PMID: 33560535 (2021) — Metabolic Profiling of Vasorelaxant Extract from Malvaviscus arboreus by LC/QTOF-MS. · Chemistry & biodiversity
- 5.PMID: 36365404 (2022) — A Mixture of Kaempferol-3-O-sambubioside and Kaempferol-3-O-sophoroside from Malvaviscus arboreus Prevents Ethanol-Induced Gastric Inflammation, Oxidative Stress, and Histologic Changes.