PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 17 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Treatment markedly decreased infiltrating eosinophils, mucus hypersecretion, ROS, Th2 cytokines (IL-4, IL-5), and total IgE in a murine model [PMID:20834153]
1,8-cineole showed remarkable anti-inflammatory effects on colitis pathogenesis in a DSS-induced mouse model [PMID:37842654]
A combination of hot water extracts (including A. compactum) showed gastroprotective effects against aspirin-induced gastric ulcers in rats [PMID:25183139]
Used for treatment of gentamicin-induced AKI in rats, affecting phospholipid metabolism [PMID:27978472]
As part of Sugemule-3 decoction, it demonstrated cardioprotective effects against isoproterenol-induced heart failure in rats via regulation of mitochondrial dynamics [PMID:34600079]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 37781022 (2023) — Antibacterial and Angiotensin I-Converting Enzyme (ACE) Inhibition Activities of Essential Oil from Java Cardamom (Amomum compactum) Fruit. · Indian journal of microbiology
- 2.PMID: 36079603 (2022) — Effects of Methods and Durations of Extraction on Total Flavonoid and Phenolic Contents and Antioxidant Activity of Java Cardamom (Amomum compactum Soland Ex Maton) Fruit. · Plants (Basel, Switzerland)
- 3.PMID: 33365677 (2019) — Complete chloroplast genome sequence of Amomum villosum. · Mitochondrial DNA. Part B, Resources
- 4.PMID: 37842654 (2023) — 1,8-cineole ameliorates colon injury by downregulating macrophage M1 polarization via inhibiting the HSP90-NLRP3-SGT1 complex. · Journal of pharmaceutical analysis
- 5.PMID: 29449878