PubMed-compiled information sheet
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Compiled from 7 PubMed articles · model: gemma4:31b
Summary
Asphodelus fistulosus is a wild plant found in regions such as Jordan and southern Australia, traditionally used for various medical conditions [PMID:35857941, PMID:33873693].
Background
Asphodelus fistulosus, also known as onion weed, is a wild plant that grows in Jordan and is a common weed in southern Australia [PMID:35857941, PMID:33873693]. It is capable of establishing in contaminated mine tailings and forming Paris-type arbuscular mycorrhiza symbioses with fungi such as Glomus coronatum [PMID:34461479, PMID:33853237].
Traditional uses
Traditionally, it is used to treat respiratory ailments, burns, and dermatomucosal infections [PMID:35857941].
Active compounds
Hydroethanol extracts of the roots contain 40 polyphenols, with major compounds including luteolin (23.89%), luteolin-7-O-β-D-glucoside (15.32%), emodin (13.49%), and feruloyltyramine (10.57%) [PMID:39097913].
Mechanism of action
The plant's root extracts exhibit antioxidant activity, specifically showing the highest activity in the ABTS•+ assay [PMID:39097913].
Clinical evidence
Evidence DBacterial infections
Aqueous flower extracts were found to be very effective against Escherichia coli (20.0 ± 0.50 mm) [PMID:35857941].
Evidence DErythrocyte membrane stability
Hydroethanol root extracts exhibited a protective effect on erythrocyte membranes at a concentration of 800 µg/mL [PMID:39097913].
Safety & adverse effects
Preliminary toxicity and cytotoxicity tests on larvae indicated that the hydroethanol root extract is non-toxic [PMID:39097913].
Evidence summary
The current evidence is limited to in vitro antibacterial assays, phytochemical profiling, and preliminary toxicity tests in larvae (Level D). No human clinical trials are provided.
PubMed sources
- 1.PMID: 35857941 (2022) — Antibacterial effect of Asphodelus fistulosus aqueous and ethanolic crude extracts on gram positive and gram negative bacteria. · Brazilian journal of biology = Revista brasleira de biologia
- 2.PMID: 34461479 (2022) — Effect of the natural establishment of two plant species on microbial activity, on the composition of the fungal community, and on the mitigation of potentially toxic elements in an abandoned mine tailing. · The Science of the total environment
- 3.PMID: 39097913 (2025) — Polyphenolic profile of Asphodelus fistulosus L. roots and evaluation of their antioxidant, anti-haemolytic activities and toxicity. · Natural product research
- 4.PMID: 33853237 (2001) — Quantitative development of Paris-type arbuscular mycorrhizas formed between Asphodelus fistulosus and Glomus coronatum. · The New phytologist
- 5.PMID: 33873693