PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Cloudberry reduced tumor number (15-30%) and tumor size by over 60%, while decreasing levels of nuclear beta-catenin and cyclin D [PMID:18296318]. It also inhibited HGF-induced cancer cell migration in human colon carcinoma cells [PMID:27270323].
Supplementation with air-dried cloudberry powder prevented the rise of systemic inflammation marker serum amyloid A (SAA) and hepatic injury marker alanine aminotransferase (ALT), and decreased expression of inflammation-related genes (Mcp1, Cxcl14, Tnfa, S100a8) [PMID:36145221].
Sanguiin H-6 and lambertianin C from cloudberry seeds inhibited in vitro biofilm development and growth of MRSA; sanguiin H-6 showed significant anti-MRSA effect in a murine wound model [PMID:34943693, PMID:37424779].
Methanol extracts of Rubus chamaemorus displayed amebicidal or amebostatic activity against pathogenic Acanthamoeba spp [PMID:16862806, PMID:19050923].
Evidence summary
PubMed sources
- 1.PMID: 25053101 (2015) — Sorbitol, Rubus fruit, and misconception. · Food chemistry
- 2.PMID: 37233639 (2023) — Comprehensive Characterization of Secondary Metabolites in Fruits and Leaves of Cloudberry (Rubus chamaemorus L.). · Metabolites
- 3.PMID: 18296318 (2008) — Berries as chemopreventive dietary constituents--a mechanistic approach with the ApcMin/+ mouse. · Asia Pacific journal of clinical nutrition
- 4.PMID: 36145221 (2022) — Cloudberry (Rubus chamaemorus L.) Supplementation Attenuates the Development of Metabolic Inflammation in a High-Fat Diet Mouse Model of Obesity. · Nutrients
- 5.PMID: 21628260 (2009) — Pollination ecology of the high latitude, dioecious cloudberry (Rubus chamaemorus; Rosaceae).