PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Active compounds in the seeds possess potent inhibitory effects on the growth of tumors [PMID:20981575]
Arctigenin from mature seeds has demonstrated therapeutic effects on various CNS diseases [PMID:37236381]
Active compounds in the seeds possess anti-inflammatory effects [PMID:20981575]
Evidence summary
PubMed sources
- 1.PMID: 20981575 (2011) — A review of the pharmacological effects of Arctium lappa (burdock). · Inflammopharmacology
- 2.PMID: 39396403 (2024) — Arctigenin ameliorates high-fat diet-induced metabolic disorders by reshaping gut microbiota and modulating GPR/HDAC3 and TLR4/NF-κB pathways. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 3.PMID: 36516694 (2023) — Arctium lappa (Burdock): Insights from ethnopharmacology potential, chemical constituents, clinical studies, pharmacological utility and nanomedicine. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- 4.PMID: 36759759 (2023) — The burdock database: a multi-omic database for Arctium lappa, a food and medicinal plant. · BMC plant biology
- 5.PMID: 37236381