PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 26 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanolic extracts of aerial parts (MECAA) accelerated wound-healing in vivo [PMID:40381088].
A mixture of oily extracts of Hypericum perforatum and Calendula arvensis was evaluated for tissue regenerating action [PMID:11482776].
Ethyl acetate extract of flowers showed cytotoxic activity against MCF-7 and MDA-MB-231 cells and inhibited cell migration [PMID:30756331].
A 10% extract demonstrated antibacterial efficacy, showing a high zone of inhibition [PMID:33223650].
Triterpenoid and sesquiterpene glycosides inhibited vesicular stomatitis virus (VSV) multiplication; some affected rhinovirus (HRV) replication [PMID:1654576, PMID:1965654].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 40381088 (2025) — Field Marigold (Calendula arvensis L.) accelerates wound-healing in vivo: role of transforming growth factor-beta1 (TGF-β1), inflammatory, and biochemical molecules. · Journal of molecular histology
- 2.PMID: 36636465 (2023) — Traditional Uses, Bioactive Compounds, and Pharmacological Investigations of Calendula arvensis L.: A Comprehensive Review. · Advances in pharmacological and pharmaceutical sciences
- 3.PMID: 35159399 (2022) — Calendula arvensis (Vaill.) L.: A Systematic Plant Analysis of the Polar Extracts from Its Organs by UHPLC-HRMS. · Foods (Basel, Switzerland)
- 4.PMID: 8277320 (1993) — Sesquiterpene glycosides from Calendula arvensis. · Journal of natural products
- 5.PMID: 30756331