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Celastrus orbiculatus
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
Invasive Asian vine naturalized in North America, used in Chinese folk medicine for arthritis and cancer.
Invasive Asian vine naturalized in North America, used in Chinese folk medicine for arthritis and cancer. Key active compounds include celastrol, wilforic acid, flavonoids.
celastrol, along with wilforic acid and flavonoids, are the primary bioactive compounds in Celastrus orbiculatus. These compounds modulates NF-κB and COX-2 inflammatory pathways, acts on pain pathways via anti-inflammatory and neuroactive effects.
Anti-inflammatory research
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Anticancer activity of celastrol
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Joint pain relief
Neuroprotection research
Traditional Chinese folk medicine for arthritis and pain
Based on traditional use; clinical evidence limited
Used in Korean medicine for cancer and inflammation
Based on traditional use; clinical evidence limited
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