PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A Clematis chinensis Osbeck extract mouthwash was effective in controlling halitosis and related oral bacteria [PMID:41771359].
A functional mouthwash containing Clematis chinensis Osbeck extract was evaluated for anticariogenic efficacy [PMID:41276841].
In animal models (CIA and AIA rats), Clematis chinensis and its monomer Clematichinenoside AR alleviated arthritis pathology and inhibited synovial angiogenesis [PMID:40020629, PMID:35421778, PMID:35032583].
Asperosaponin VI from C. chinensis mitigated mitochondrial dysfunction and chondrocyte apoptosis in a rat model [PMID:40702216].
Evidence summary
PubMed sources
- 1.PMID: 40020629 (2025) — Clematichinenoside AR alleviates rheumatoid arthritis by inhibiting synovial angiogenesis through the HIF-1α/VEGFA/ANG2 axis. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 2.PMID: 8768328 (1996) — Saponins from Clematis chinensis. · Phytochemistry
- 3.PMID: 7786477 (1995) — Triterpenoid saponins from Clematis chinensis. · Phytochemistry
- 4.PMID: 40702216 (2025) — Asperosaponin VI mitigates mitochondrial dysfunction and chondrocyte apoptosis in osteoarthritis by modulating the AMPK-SIRT3 pathway. · Cell biology and toxicology
- 5.PMID: 26670420 (2016) — Renal toxic ingredients and their toxicology from traditional Chinese medicine.