PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ingestion of 15g of freeze-dried powder in juice significantly suppressed the elevation of postprandial blood glucose levels in healthy young male adults [PMID:15830920].
In mice, a 4 mg/kg dose of molokhia leaf polysaccharide fraction (MPF) significantly decreased body weight, adipocyte size, serum triglycerides, and LDL cholesterol, while decreasing gut permeability [PMID:35121021].
In C57BL/6J mice, 100 mg/kg of water-soluble extract (WM) significantly lowered body weight, gut permeability, and hepatic lipid accumulation [PMID:32302714].
Dietary supplementation (100 mg/g) in diabetic rats reversed decreased hepatic delta-aminolevulinic acid dehydratase activity and increased catalase and SOD activity [PMID:31368580].
Seed extract was used in buccoadhesive films to treat ulcers, with in vivo models showing potential for wound healing via targets such as TGF-beta, TNF-alpha, and IL-1 [PMID:36296628].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 36540263 (2022) — Pharmacological and phytochemical biodiversity of Corchorus olitorius. · RSC advances
- 2.PMID: 35121021 (2022) — Dietary rhamnogalacturonan-Ⅰ rich extracts of molokhia ameliorate high fat diet-induced obesity and gut dysbiosis. · The Journal of nutritional biochemistry
- 3.PMID: 32302714 (2020) — Molokhia leaf extract prevents gut inflammation and obesity. · Journal of ethnopharmacology
- 4.PMID: 37090773 (2023) — Corchorus olitorius extract exhibit anti-hyperglycemic and anti-inflammatory properties in rodent models of obesity and diabetes mellitus. · Frontiers in nutrition
- 5.PMID: 36129373 (2022) — Multi-omics provides new insights into the domestication and improvement of dark jute (Corchorus olitorius).