PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 7 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanol twig extract counteracted LPS-induced increases in colon nitrite, prostaglandin E2, and 8-iso-PGF2α [PMID:31353569]
Leaf and fruit extracts inhibited α-glucosidase and α-amylase and nonenzymatic protein glycation [PMID:36296676]
Extracts showed protective effects against H2O2-induced lactate dehydrogenase activity and TNF-α gene expression [PMID:31353569]
Evidence summary
PubMed sources
- 1.PMID: 31353569 (2019) — Protective effects of Cotoneaster integerrimus on in vitro and ex-vivo models of H2 O2 -induced lactate dehydrogenase activity in HCT116 cell and on lipopolysaccharide-induced inflammation in rat colon. · Journal of food biochemistry
- 2.PMID: 36296676 (2022) — The Inhibition of α-Glucosidase, α-Amylase and Protein Glycation by Phenolic Extracts of Cotoneaster bullatus, Cotoneaster zabelii, and Cotoneaster integerrimus Leaves and Fruits: Focus on Anti-Hyperglycemic Activity and Kinetic Parameters. · Molecules (Basel, Switzerland)
- 3.PMID: 34961270 (2021) — Genome Size, Cytotype Diversity and Reproductive Mode Variation of Cotoneaster integerrimus (Rosaceae) from the Balkans. · Plants (Basel, Switzerland)
- 4.PMID: 41463510 (2025) — Distribution and Ecological Traits of Cotoneaster integerrimus in South Korea. · Biology
- 5.PMID: 35413069