PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Cupuacu seed extract significantly stimulated cell proliferation and migration and promoted a reparative gene expression profile in vitro [PMID:35057102].
Cupuacu butter affects the cell number of human skin fibroblasts and the expression profiles of growth factors including bFGF, SCF, VEGF, HGF, FGF7, and EGF [PMID:30370321].
Evidence summary
PubMed sources
- 1.PMID: 36553708 (2022) — Theobroma cacao and Theobroma grandiflorum: Botany, Composition and Pharmacological Activities of Pods and Seeds. · Foods (Basel, Switzerland)
- 2.PMID: 38837946 (2024) — Genomic decoding of Theobroma grandiflorum (cupuassu) at chromosomal scale: evolutionary insights for horticultural innovation. · GigaScience
- 3.PMID: 35057102 (2022) — Skin Regenerative Potential of Cupuaçu Seed Extract (Theobroma grandiflorum), a Native Fruit from the Amazon: Development of a Topical Formulation Based on Chitosan-Coated Nanocapsules. · Pharmaceutics
- 4.PMID: 36984807 (2023) — Assessing the Effectiveness of Chemical Marker Extraction from Amazonian Plant Cupuassu (Theobroma grandiflorum) by PSI-HRMS/MS and LC-HRMS/MS. · Metabolites
- 5.PMID: 32872250