PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Polysaccharides (CSP) and flavonoid-enriched fractions show promising anti-diabetic activity and improvement of insulin sensitivity [PMID:40058318, PMID:39032280, PMID:34052560].
Flavonoids and polysaccharides may alleviate reproductive injury, enhance sperm count and motility, and restore serum testosterone levels [PMID:39239657, PMID:41276052].
Total flavonoids attenuated cognitive defects by activating BDNF/TrkB signaling [PMID:37851367].
C. songaricum and its derived compounds (luteolin, gallic acid) inhibit rat BPH via phytoestrogenic or phytoandrogenic activities [PMID:30708032].
Water and alcohol extracts of C. coccineum demonstrated high capacity in decreasing cancer cell viability in five different cell lines [PMID:30261584].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 23845540 (2013) — Chemical constituents and pharmacologic actions of Cynomorium plants. · Chinese journal of natural medicines
- 2.PMID: 30261584 (2018) — Anticancer Activity of Cynomorium coccineum. · Cancers
- 3.PMID: 23369691 (2013) — The genus Cynomorium in China: an ethnopharmacological and phytochemical review. · Journal of ethnopharmacology
- 4.PMID: 38474452 (2024) — Research Progress in Traditional Applications, Phytochemistry, Pharmacology, and Safety Evaluation of Cynomorium songaricum. · Molecules (Basel, Switzerland)
- 5.PMID: 30949225 (2019) — Toxicity Assessment of Chinese Herbal Medicine Cynomorium songaricum Rupr.