PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Water and alcohol extracts decreased viability of five cancer cell lines [PMID:30261584]; fixed oil inhibited growth of B16F10 melanoma and Caco-2 colon cancer cells [PMID:25629557, 22809475]; methanolic extracts showed antiproliferative activity against human leukaemia-derived cell lines [PMID:31621410].
Aqueous extracts increased sperm count, motility, and spermatogenesis in rats [PMID:10353171, 11282435] and provided protective effects against aluminum chloride-induced reproductive toxicity [PMID:41665028].
Water extracts in immature rats elicited significant changes in gonadotrophin levels and increased ovarian weight and folliculogenesis [PMID:10861976].
Triterpenoids from C. coccineum subsp. songaricum showed neuroprotective effects against glutamate-induced or oxygen-glucose deprivation-induced SK-N-SH cell death [PMID:35259348].
Fresh juice and water-soluble fractions exhibited significant blood pressure lowering activity in dogs [PMID:683693].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 30261584 (2018) — Anticancer Activity of Cynomorium coccineum. · Cancers
- 2.PMID: 31678417 (2020) — Astringent drugs for bleedings and diarrhoea: The history of Cynomorium coccineum (Maltese Mushroom). · Journal of ethnopharmacology
- 3.PMID: 31394783 (2019) — The Modern Use of an Ancient Plant: Exploring the Antioxidant and Nutraceutical Potential of the Maltese Mushroom (Cynomorium Coccineum L.). · Antioxidants (Basel, Switzerland)
- 4.PMID: 35259348 (2022) — Structures and neuroprotective activities of triterpenoids from Cynomorium coccineum subsp. songaricum (Rupr.) J. Leonard. · Phytochemistry
- 5.PMID: 30949225 (2019) — Toxicity Assessment of Chinese Herbal Medicine Cynomorium songaricum Rupr.