PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Yam and its extracts have been identified as beneficial in controlling glycaemia in rodent models [PMID:34521490].
D. polystachya root extract attenuated osteoclastogenesis and ovariectomy-induced bone loss in rats [PMID:41173080].
Chinese yam polysaccharides (CYP/CYP-A) reduced colon shortening, mitigated crypt architectural distortion, and suppressed pro-inflammatory cytokines in mice [PMID:40498533, PMID:40360104].
Chinese yam polysaccharide synergistically inhibited tumour growth when combined with αPD-1 monoclonal antibody in xenograft models [PMID:40267869].
Chinese yam polysaccharide (SYDT) significantly protected renal function and alleviated fibrosis in rats [PMID:39603894].
Evidence summary
PubMed sources
- 1.PMID: 39303509 (2024) — Shenqi Pill alleviates acetaminophen-induced liver injury: a comprehensive strategy of network pharmacology and spectrum-effect relationship reveals mechanisms and active components. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 2.PMID: 40267869 (2025) — Chinese yam polysaccharide enhances anti-PD-1 immunotherapy in colorectal cancer through alterations in the gut microbiota and metabolites. · International journal of biological macromolecules
- 3.PMID: 38790726 (2024) — A Frontier Review of Nutraceutical Chinese Yam. · Foods (Basel, Switzerland)
- 4.PMID: 37215221 (2023) — Transcriptomic analysis of Chinese yam (Dioscorea polystachya Turcz.) variants indicates brassinosteroid involvement in tuber development. · Frontiers in nutrition
- 5.PMID: 34521490