PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Donkey-hide gelatin-derived carbon dots promoted proliferation and erythroid differentiation of hematopoietic stem cells and alleviated oxidative stress in AA mice [PMID: 39772431].
Water extracts of donkey-hide gelatin significantly decreased skin symptom scores and inhibited pro-inflammatory cytokines (IL-6, IL-8) in mice and keratinocytes [PMID: 35694270, 37432237].
Ejiao alleviated sarcopenia in an aging rat model by modulating AKT/mTOR/Foxo3a and AMPK pathways [PMID: 41161622].
Donkey-hide gelatin hydrolysates enhanced hematopoiesis and iron homeostasis, elevating hemoglobin by 44% in a rat model [PMID: 41298488].
Low molecular weight peptides of E-Jiao demonstrated blood-supplementing effects in blood-deficient zebrafish and mouse models [PMID: 38904003].
Evidence summary
PubMed sources
- 1.PMID: 39772431 (2025) — Donkey-Hide Gelatin-Derived Carbon Dots Activate Erythropoiesis and Eliminate Oxidative Stress for Aplastic Anemia Treatment. · ACS nano
- 2.PMID: 35960756 (2022) — Species-specific identification of donkey-hide gelatin and its adulterants using marker peptides. · PloS one
- 3.PMID: 35694270 (2022) — Inhibitory Effects of Donkey Hide Gelatin on DNCB-Induced Atopic Dermatitis in NC/Nga Mice. · Frontiers in pharmacology
- 4.PMID: 38138465 (2023) — Structural Characteristics and Antioxidant Mechanism of Donkey-Hide Gelatin Peptides by Molecular Dynamics Simulation. · Molecules (Basel, Switzerland)
- 5.PMID: 36117504 (2021) — Collagen derived species-specific peptides for distinguishing donkey-hide gelatin (Asini Corii Colla).