PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 19 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Extracts from leaves and flowering heads significantly reduced lipid peroxidation and oxidative stress in diclofenac-induced rat models, while benefiting the activity of drug-metabolizing enzymes ethylmorphine-N-demetylase and aniline hydroxylase [PMID:37373147]
Isolated thiophenes demonstrated antibacterial activity against Staphylococcus aureus and Escherichia coli, and antifungal activity against Candida albicans and Colletotrichum species [PMID:30813374, PMID:16506815]
Evidence summary
PubMed sources
- 1.PMID: 37373147 (2023) — Antioxidant and Hepatoprotective Potential of Echinops ritro L. Extracts on Induced Oxidative Stress In Vitro/In Vivo. · International journal of molecular sciences
- 2.PMID: 30813374 (2019) — Novel Substituted Thiophenes and Sulf-Polyacetylene Ester from Echinops ritro L. · Molecules (Basel, Switzerland)
- 3.PMID: 39084763 (2024) — The larvicidal efficacy and mechanism of action of 5-Ethenyl-2,2'-bithiophene extracted from Echinops ritro on Aedes aegypti larvae. · Pesticide biochemistry and physiology
- 4.PMID: 16506815 (2006) — Antifungal activity of thiophenes from Echinops ritro. · Journal of agricultural and food chemistry
- 5.PMID: 16449376 (2006)