PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 18 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Used in pharmaceutical syrups for children to treat feverishness accompanying upper respiratory tract infections [PMID: 27162290].
Aqueous extracts potently inhibit proinflammatory activities of major virulence factors from Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in vitro [PMID: 16460254].
Aqueous elder extracts induce ABCA1 expression and reduce cholesteryl ester accumulation in aggregated LDL-induced foam cells [PMID: 38347122].
Narcissoside from elderflowers reduced ROS generation and degeneration of dopaminergic neurons in C. elegans and SH-SY5Y cells [PMID: 36358461].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 36559324 (2022) — Comparison of the Formulation, Stability and Biological Effects of Hydrophilic Extracts from Black Elder Flowers (Sambucus nigra L.). · Pharmaceutics
- 2.PMID: 27162290 (2016) — [Not Available]. · Wiadomosci lekarskie (Warsaw, Poland : 1960)
- 3.PMID: 38347122 (2024) — Elder (Sambucus nigra), identified by high-content screening, counteracts foam cell formation without promoting hepatic lipogenesis. · Scientific reports
- 4.PMID: 34443417 (2021) — Biological Actions and Molecular Mechanisms of Sambucus nigra L. in Neurodegeneration: A Cell Culture Approach. · Molecules (Basel, Switzerland)
- 5.PMID: 34356325 (2021) — The Physicochemical and Antioxidant Properties of Sambucus nigra L. and Sambucus nigra Haschberg during Growth Phases: From Buds to Ripening.