PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Active compounds
Mechanism of action
Clinical evidence
Phenol-rich fruit extracts (10-200 μg/mL) protect human red blood cells from oxidative stress and cellular toxicity induced by HgCl2, with peel extracts showing greater effect than pulp [PMID:31336755]
Topical application of 5% w/w fruit extract ointment significantly increased wound closure, collagen deposition, and the volume of new epidermis and dermis compared to non-treated groups [PMID:36004938]
Methanolic leaf and fruit extracts showed dose-dependent antidepressant activity in forced swimming and tail suspension tests, with leaf extract showing superior activity to imipramine in the forced swimming test at 800 mg/kg [PMID:26214790]
Oral administration of fruit extract (400 mg/kg) ameliorated sperm count, morphology, motility, and viability, and increased levels of LH, FSH, prolactin, and testosterone [PMID:33355948]
Silver nanoparticles based on fruit extracts reduced the proliferation index of T. gondii tachyzoites in Vero cells and increased survival rates in infected mice [PMID:37330943, PMID:30087799]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 31336755 (2019) — Phenol-Rich Feijoa sellowiana (Pineapple Guava) Extracts Protect Human Red Blood Cells from Mercury-Induced Cellular Toxicity. · Antioxidants (Basel, Switzerland)
- 2.PMID: 37151701 (2023) — Anticoagulant effect of Feijoa sellowiana extracts generated by different biotechnological techniques. · Heliyon
- 3.PMID: 35938449 (2022) — Chemical Composition, Antiaging Activities and Molecular Docking Studies of Essential Oils from Acca sellowiana (Feijoa). · Chemistry & biodiversity
- 4.PMID: 38298607 (2023) — Establishment of feijoa (Acca sellowiana) callus and cell suspension cultures and identification of arctigenin - a high value bioactive compound. · Frontiers in plant science
- 5.PMID: 31480592