PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 29 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A meta-analysis of seven RCTs favored fennel for improving menopausal symptoms, although no beneficial effects were seen for sexual function, quality of life, or psychological health [PMID:33725577].
Meta-analysis of 12 studies showed that F. vulgare intake significantly decreased the intensity of dysmenorrhea compared to placebo [PMID:34187122].
In a randomized, placebo-controlled trial, fennel significantly decreased the number of ovarian follicles compared to placebo [PMID:37655000].
Two small studies found increases in milk volume, fat content, and infant weight gain, though no increase in serum prolactin was observed [PMID:30000852].
One meta-analysis revealed fennel oil significantly increased mean bleeding in the first menstrual cycle, but had no significant effect in the second cycle [PMID:31080784].
Safety & adverse effects
Pregnancy & lactation
Evidence summary
PubMed sources
- 1.PMID: 30000852 (2006) — Foeniculum vulgare Mill: a review of its botany, phytochemistry, pharmacology, contemporary application, and toxicology. · BioMed research international
- 2.PMID: 36803269 (2024) — Exploring fennel (Foeniculum vulgare): Composition, functional properties, potential health benefits, and safety. · Critical reviews in food science and nutrition
- 3.PMID: 40892151 (2025) — Advanced techniques and applications in fennel (Foeniculum vulgare Mill.) breeding. · Molecular genetics and genomics : MGG
- 4.PMID: 31080784 (2019) — Foeniculum vulgare as Valuable Plant in Management of Women's Health. · Journal of menopausal medicine
- 5.PMID: 40335931 (2025)