PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 17 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Flavones gnaphaliin A and B from Gnaphalium liebmannii showed potent relaxant properties on guinea pig tracheal smooth muscle, exceeding the potency of aminophylline in that model [PMID:19505084].
Seven flavones from Pseudognaphalium liebmannii (excluding 5-hydroxy-3,7-dimethoxyflavone and 3,5,7-trimethoxyflavone) demonstrated relaxant effects on guinea pig tracheal preparations [PMID:38189356].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 3158474 (1985) — Occupational dermatitis from Gordolobo (Mullein). · Contact dermatitis
- 2.PMID: 38692216 (2024) — Chemical profiling and quantification of flavones in several Pseudognaphalium and Gnaphalium species of Mexican gordolobo using UHPLC/PDA/MS. · Journal of pharmaceutical and biomedical analysis
- 3.PMID: 35152008 (2022) — A semi-targeted NMR-based chemical profiling of retail samples of Mexican gordolobo. · Journal of pharmaceutical and biomedical analysis
- 4.PMID: 17026698 (2006) — Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). · Contact dermatitis
- 5.PMID: 19505084 (2009) — Solving the confusion of gnaphaliin structure: gnaphaliin A and gnaphaliin B identified as active principles of Gnaphalium liebmannii with tracheal smooth muscle relaxant properties.