PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 26 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
The German Commission E approved extracts of hawthorn leaf with flower for heart failure graded stage II (NYHA), though systematic reviews assess the benefits and harms of these extracts compared to placebo [PMID:18254076]
A randomized controlled trial of 1200 mg daily hawthorn extract for 16 weeks showed a significant group difference in mean diastolic blood pressure [PMID:16762125]
In diabetic subjects with chronic CHD, a micronized flower and leaf preparation (400 mg three times daily) significantly decreased neutrophil elastase (NE) over 6 months [PMID:21242072]
A supplement containing C. laevigata fruits, S. baicalensis, magnesium, and chromium significantly improved performance on tasks of attention and working memory in stressed adults [PMID:41194549]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 41194549 (2025) — Effects of a Scutellaria baicalensis/Crataegus laevigata, magnesium and chromium supplement on stressed individuals: A randomised, double-blind, placebo-controlled, crossover trial. · Journal of psychopharmacology (Oxford, England)
- 2.PMID: 32138258 (2020) — Assessment of Antioxidants in Selected Plant Rootstocks. · Antioxidants (Basel, Switzerland)
- 3.PMID: 18254076 (2008) — Hawthorn extract for treating chronic heart failure. · The Cochrane database of systematic reviews
- 4.PMID: 37176893 (2023) — Flowers and Inflorescences of Selected Medicinal Plants as a Source of Triterpenoids and Phytosterols. · Plants (Basel, Switzerland)
- 5.PMID: 21242072 (2011)