PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 27 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Evaluated for efficacy in the dissolution of stones and improvement of clinical symptoms in a prospective cohort study [PMID:36098361].
A multi-center RCT on Child Compound Endothelium Corneum (CCEC) showed no statistical difference in recovery rate of anorexia or weight change compared to the control group after 21 days [PMID:34047133].
A case report showed complete removal of a ureteral stone after therapy with a combination of herbs including Endothelium Corneum Gigeriae Galli [PMID:29458917].
In rat models, Child compound Endothelium corneum (CCEC) significantly enhanced gastric emptying and small intestinal transit and suppressed gastrointestinal microinflammation [PMID:31082513].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 36098361 (2022) — Oral Endothelium Corneum Gigeriae Galli Therapy for Pancreatic Duct Stones: A Prospective Cohort Study. · The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
- 2.PMID: 40771715 (2025) — Research progress on the chemical composition of galli gigeriae endothelium corneum. · Frontiers in chemistry
- 3.PMID: 30194056 (2019) — Endothelium corneum gigeriae galli extract inhibits calcium oxalate formation and exerts anti-urolithic effects. · Journal of ethnopharmacology
- 4.PMID: 39041079 (2024) — [Authenticity discrimination for Galli Gigerii Endothelium Corneum based on UPLC-MS/MS and peptidomics]. · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
- 5.PMID: 33593395