PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 9 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanol extract (50 mg/kg/day for 14 days in rats) effectively suppressed disturbed cardiac response to perfusion pressure changes and reduced prooxidants [PMID:37372007]
Methanol extract (500 mg/kg for 4 weeks in spontaneously hypertensive rats) showed protective effects against injury with an emphasis on the role of oxidative stress [PMID:30863479]
Aqueous extract/decoction demonstrated cytotoxicity across multiple cell lines (HLaC78, FADU, Hep-2, HLaC79) and inhibited cell invasion/motility [PMID:25017936, PMID:24366449]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 37372007 (2023) — Lady's Bedstraw as a Powerful Antioxidant for Attenuation of Doxorubicin-Induced Cardiotoxicity. · Antioxidants (Basel, Switzerland)
- 2.PMID: 30863479 (2019) — Protective Effects of Galium verum L. Extract against Cardiac Ischemia/Reperfusion Injury in Spontaneously Hypertensive Rats. · Oxidative medicine and cellular longevity
- 3.PMID: 25017936 (2014) — Galium verum aqueous extract strongly inhibits the motility of head and neck cancer cell lines and protects mucosal keratinocytes against toxic DNA damage. · Oncology reports
- 4.PMID: 24366449 (2014) — Effect of Galium verum aqueous extract on growth, motility and gene expression in drug-sensitive and -resistant laryngeal carcinoma cell lines. · International journal of oncology
- 5.PMID: 29339117