PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Extracts and yunnaneic acid B diminished oxidative damage to blood plasma proteins and lipids and improved non-enzymatic antioxidant capacity in vitro [PMID:33530389, PMID:28453265].
Phenolic-rich fractions showed bacteriostatic effects (MIC 1-2 mg/mL) and targeted virulence rather than viability, decreasing S. aureus adhesion [PMID:30909529].
Literature review indicates that Pulmonaria officinalis possesses anti-coagulant activity [PMID:28866770].
Safety & adverse effects
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 28866770 (2017) — Anti-coagulant activity of plants: mini review. · Journal of thrombosis and thrombolysis
- 2.PMID: 33530389 (2021) — Pulmonaria obscura and Pulmonaria officinalis Extracts as Mitigators of Peroxynitrite-Induced Oxidative Stress and Cyclooxygenase-2 Inhibitors-In Vitro and In Silico Studies. · Molecules (Basel, Switzerland)
- 3.PMID: 30200600 (2018) — Novel Phenolic Constituents of Pulmonaria officinalis L. LC-MS/MS Comparison of Spring and Autumn Metabolite Profiles. · Molecules (Basel, Switzerland)
- 4.PMID: 41012471 (2025) — Assessment of Antioxidant Activity and Dose-Dependent Effect on Genotoxicity/Antigenotoxicity of Pulmonaria officinalis Ethanolic Extract. · Pharmaceutics
- 5.PMID: 29686522