PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 24 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Red maca reduced prostate size and weight in rats and mice with testosterone-induced BPH, showing a dose-dependent effect that in some studies was superior to finasteride [PMID:15661081, 17289361, 18477205, 24718534].
Red maca reversed the effects of ovariectomy by increasing trabecular bone area in the second lumbar vertebra of rats without showing estrogenic effects on the uterus [PMID:20616517, 24718534].
Red maca lipophilic extract attenuated dexamethasone-induced muscle atrophy in vitro and in vivo [PMID:38340399].
Lyophilized aqueous extract of red maca prevented the increase of MDA levels in erythrocytes, brain, and liver, and lowered ALT and AST levels in rats treated with acrylamide [PMID:35932411].
Topical administration of red maca extract promoted skin wound healing in mice [PMID:28846044] and provided the highest antioxidant activity and photoprotection against UVB-induced epidermal damage among maca varieties [PMID:21781063].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 20090350 (2009) — Lepidium meyenii (Maca): a plant from the highlands of Peru--from tradition to science. · Forschende Komplementarmedizin (2006)
- 2.PMID: 24718534 (2014) — [Maca (Lepidium meyenii Walp), a review of its biological properties]. · Revista peruana de medicina experimental y salud publica
- 3.PMID: 27548190 (2016) — Acceptability, Safety, and Efficacy of Oral Administration of Extracts of Black or Red Maca (Lepidium meyenii) in Adult Human Subjects: A Randomized, Double-Blind, Placebo-Controlled Study. · Pharmaceuticals (Basel, Switzerland)
- 4.PMID: 15661081 (2005) — Red maca (Lepidium meyenii) reduced prostate size in rats. · Reproductive biology and endocrinology : RB&E
- 5.PMID: 38340399 (2024)