Question 1

How does Padauk bark work to lower blood sugar?

Accepted Answer

Padauk bark (Pterocarpus macrocarpus) contains active compounds including pterostilbene and flavonoids that may support glucose metabolism through multiple pathways. These compounds demonstrate antioxidant activity and may help protect pancreatic beta cells from oxidative damage. Traditional use and preliminary research suggest potential effects on glucose uptake and insulin sensitivity, though the exact mechanism requires further clinical investigation. Evidence level: C.

Question 2

Can I take Padauk bark with diabetes medications?

Accepted Answer

Padauk bark should not be combined with conventional diabetes medications without medical supervision. The herb has hypoglycemic properties that may cause additive effects when taken with antidiabetic drugs like metformin, sulfonylureas, or insulin, potentially leading to dangerously low blood sugar (hypoglycemia). Patients on diabetes medications should consult a healthcare provider before using Padauk bark. Evidence level: C.

Question 3

What is the recommended dosage for Padauk bark?

Accepted Answer

The typical adult dosage for Padauk bark is 2-4 grams of dried bark prepared as a decoction daily, or 200-400mg of standardized extract. Traditional preparations involve simmering the bark in water for 10-15 minutes. Dosage should be divided throughout the day and taken with food to reduce gastrointestinal upset. Consult a qualified practitioner for personalized dosing. Evidence level: Traditional/C.

Question 4

Is Padauk bark safe during pregnancy?

Accepted Answer

Padauk bark is considered unsafe during pregnancy and breastfeeding. The herb has documented hypoglycemic effects and active compounds that may affect fetal development or maternal glucose metabolism. There is insufficient safety data to support use during pregnancy. Women who are pregnant, planning to become pregnant, or breastfeeding should avoid Padauk bark entirely. Evidence level: C/Traditional.

Question 5

What are the side effects of Padauk bark?

Accepted Answer

Padauk bark may cause mild gastrointestinal upset including nausea, stomach discomfort, or loose stools in some individuals. The primary safety concern is hypoglycemia (low blood sugar), particularly when taken in high doses or combined with other glucose-lowering agents. Symptoms of hypoglycemia include dizziness, sweating, confusion, and weakness. Discontinue use if adverse effects occur. Evidence level: C/Traditional.

Question 6

What is Padauk bark used for in traditional medicine?

Accepted Answer

Padauk bark has been used in Burmese traditional medicine primarily for managing diabetes and blood sugar regulation. Additional traditional applications include treating skin conditions such as wounds, infections, and dermatological disorders, as well as addressing inflammatory diseases. The bark contains pterostilbene, flavonoids, and tannins that contribute to its antioxidant and anti-inflammatory properties. Evidence level: C/Traditional.

Padauk Bark

Sources & Citations

Physalis peruviana

Ipomoea Batatas Leaf

Cassia auriculata

Summary

Background

Active compounds

Mechanism of action

Clinical evidence

Safety & adverse effects

Evidence summary

PubMed sources

Government sources