PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A triple-blind clinical trial investigated the therapeutic impact of a dodder and polypody herbal product (DPHP) in patients taking fluvoxamine [PMID:40848906].
In vivo and in vitro mouse models showed that P. vulgare extract was more effective than control/vehicle groups in new vascular, epidermal, and granulation tissue organization, with stronger PDGF, VEGF, and collagen staining [PMID:33717624].
Ethanolic extract was studied for cytotoxic effects on A375 melanoma cells [PMID:36708577].
Rhizome aqueous extract was found to enhance the activity of ciprofloxacin and photodynamic therapy (PDT) against uropathogenic E. coli [PMID:34959499].
Rhizomes were evaluated for in vitro cholinesterase inhibitory activity [PMID:28278615].
Evidence summary
PubMed sources
- 1.PMID: 21803067 (2011) — Ecdysteroids from Polypodium vulgare L. · Steroids
- 2.PMID: 31527294 (2019) — A review on the management of asthma in the Avicenna's Canon of Medicine. · Journal of complementary & integrative medicine
- 3.PMID: 31538499 (2021) — Isolation and structural determination of flavan-3-ol derivatives from the Polypodium vulgare L. rhizomes water extract. · Natural product research
- 4.PMID: 36708577 (2023) — Cytotoxic Effects of Ethanolic Extract of Polypodium Vulgare on Human Malignant Melanoma Cell Line. · Asian Pacific journal of cancer prevention : APJCP
- 5.PMID: 33717624 (2020) — An Alternative Approach Wound Healing Field with Polypodium Vulgare.