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Populus tremuloides
This herb is NOT recommended during pregnancy due to potential risks to the developing fetus.
This herb is NOT recommended while breastfeeding as effects on infants are unknown.
Consult your healthcare provider before use.
Widespread North American tree whose bark was used by many indigenous peoples and early American medicine for fever, pain, and urinary conditions.
Widespread North American tree whose bark was used by many indigenous peoples and early American medicine for fever, pain, and urinary conditions. Key active compounds include salicin, populin, isosalipurposide.
salicin, along with populin and isosalipurposide, are the primary bioactive compounds in Poplar Bark. These compounds modulates NF-κB and COX-2 inflammatory pathways, acts on pain pathways via anti-inflammatory and neuroactive effects.
Analgesic via salicylates
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Anti-inflammatory
Limited clinical evidence; primarily supported by traditional use and preliminary studies
Antipyretic
Astringent
Fever and pain in many Native American traditions
Based on traditional use; clinical evidence limited
Urinary conditions in Ojibwe and Cree medicine
Based on traditional use; clinical evidence limited
Rheumatic conditions
Based on traditional use; clinical evidence limited
Diarrhea treatment
Based on traditional use; clinical evidence limited
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