PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A combination including Inula racemosa, Commiphora mukul, Centella asiatica, and Hypericum perforatum showed significant correction in lipid profile (including triglycerides), blood pressure, and psychological factors like anxiety and depression over 6 months [PMID:22556998].
Root extract demonstrated hepatoprotective potential against diethylnitrosamine (DEN) induced hepatic damage in a murine model [PMID:40638963].
Isoalantolactone showed dose-dependent reduction in cell viability and induction of apoptosis in testicular cancer cells in vitro [PMID:39382942].
Aqueous root extract improved survival of Normal Kidney Epithelium cells and increased whole-body survival in mice exposed to gamma-radiation [PMID:30998083].
Methanol extract of Inula racemosa showed 90.33% mycelial inhibition against the brown spot pathogen Bipolaris oryzae in vitro [PMID:38977720].
Evidence summary
PubMed sources
- 1.PMID: 9855567 (1998) — Botanical influences on cardiovascular disease. · Alternative medicine review : a journal of clinical therapeutic
- 2.PMID: 34600078 (2022) — Ethnopharmacology, phytochemistry, agrotechnology, and conservation of Inula racemosa Hook f. - A critically endangered medicinal plant of the western Himalaya. · Journal of ethnopharmacology
- 3.PMID: 24288468 (2013) — Targeting apoptosis pathways in cancer with alantolactone and isoalantolactone. · TheScientificWorldJournal
- 4.PMID: 21623523 (2011) — Sesquiterpenoids from Inula racemosa. · Journal of Asian natural products research
- 5.PMID: 22556998 (2000) — Individuals at Risk of Coronary Heart Disease (CHD), its Prevention and Management by an Indigenous Compound.