PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Essential-oil extracts significantly reduced serum and hepatic total cholesterol, triglycerides, and LDL levels while increasing HDL levels in high-fat-diet rats [PMID:28911557].
Extracts (particularly 70% methanol fraction) exhibit inhibitory effects on platelet aggregation induced by ADP, arachidonic acid, and collagen [PMID:42180572].
Crude polysaccharides and specific fractions (MT-95ET) reduced myocardial injury and fibrosis in I/R rat models and protected H9c2 myocardial cells in vitro [PMID:38432275, 40728972, 38094023].
Rakkyo-derived fructan stimulates the synthesis of collagen and hyaluronan in human dermal fibroblasts [PMID:41754166].
Specific steroidal saponins (e.g., A-24) show dose-dependent cytotoxicity and induce apoptosis and autophagy in human gastric adenocarcinoma cell lines [PMID:42234991, 32485185].
Evidence summary
PubMed sources
- 1.PMID: 38094023 (2023) — Two new phenolic amides from Allium chinense. · Chinese herbal medicines
- 2.PMID: 33803393 (2021) — Effect of Dietary Supplementation of Immunobiotic Lactiplantibacillusplantarum N14 Fermented Rakkyo (Allium chinense) Pickled Juice on the Immunocompetence and Production Performance of Pigs. · Animals : an open access journal from MDPI
- 3.PMID: 36985457 (2023) — Allii Macrostemonis Bulbus: A Comprehensive Review of Ethnopharmacology, Phytochemistry and Pharmacology. · Molecules (Basel, Switzerland)
- 4.PMID: 41754166 (2026) — Rakkyo (Allium chinense)-Derived Fructan Stimulates Collagen and Hyaluronan Synthesis in Human Dermal Fibroblasts. · Nutrients
- 5.PMID: 11312859 (2001)