PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Treatment with a Rosa gallica petal extract (RPE) formulation significantly enhanced skin brightness (L* value) in volunteers [PMID:32609563]
A double-blinded clinical study demonstrated that RPE treatment significantly improved hydration levels in human skin [PMID:36573713]
Oral administration in mice prevented UVB-mediated skin wrinkle formation and loss of collagen/keratin fibers [PMID:34829534]
In mice subjected to chronic stress, R. gallica extract reduced the decrease in activity compared to controls, though no significant effect was seen in non-stressed mice [PMID:31431930]
RPE inhibited growth, migration, and invasion of A549 cells via EGFR-MAPK and mTOR-Akt signaling pathways [PMID:33158043]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 33478154 (2021) — Rose Flowers-A Delicate Perfume or a Natural Healer? · Biomolecules
- 2.PMID: 37631190 (2023) — Detailed Metabolic Characterization of Flowers and Hips of Rosa gallica L. Grown in Open Nature. · Plants (Basel, Switzerland)
- 3.PMID: 31431930 (2019) — Anti-stress effects of the hydroalcoholic extract of Rosa gallica officinalis in mice. · Heliyon
- 4.PMID: 34829534 (2021) — Oral Administration of Rosa gallica Prevents UVB-Induced Skin Aging through Targeting the c-Raf Signaling Axis. · Antioxidants (Basel, Switzerland)
- 5.PMID: 32609563 (2020) — Rose Petal Extract (Rosa gallica) Exerts Skin Whitening and Anti-Skin Wrinkle Effects.