PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Topical administration of leaf extract improved hair regrowth in testosterone-treated mice and inhibited 5α-reductase [PMID:22517595]
Extract inhibited proliferation and survival of both androgen-sensitive (22RV1) and androgen-insensitive (PC-3) cells without affecting normal prostate epithelial cells [PMID:33152908, PMID:24598693]
In rats fed a high-fat diet, extract reduced liver fat percentage, total liver cholesterol, and triglycerides, while increasing plasma HDL and GLP-1 [PMID:37755254]
Extract demonstrated inhibition of HSV-1 and HSV-2 plaque formation, with complete inhibition at 50 μg/ml [PMID:32469389]
Extract showed antibiofilm effects against various Candida species similar to nystatin [PMID:33950151] and inhibitory activity against B. subtilis and P. aeruginosa [PMID:40043926].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 30621719 (2019) — Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent. · Journal of biomedical science
- 2.PMID: 32963731 (2020) — Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders. · Iranian journal of basic medical sciences
- 3.PMID: 22517595 (2013) — Promotion of hair growth by Rosmarinus officinalis leaf extract. · Phytotherapy research : PTR
- 4.PMID: 26452641 (2015) — Rosemary (Rosmarinus officinalis L.) Extract as a Potential Complementary Agent in Anticancer Therapy. · Nutrition and cancer
- 5.PMID: 30328397 (2018) — Rosmarinic Acid as Potential Anti-Inflammatory Agent.