PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Przewaquinone A inhibits Angiotensin II-induced endothelial diastolic dysfunction [PMID:39096544]
Przewaquinone A suppresses the growth and metastasis of melanoma cells [PMID:40311593]
Total phenolic acid extract (SPE) significantly reduced urine protein excretion [PMID:29025319]
High-dose SPE significantly decreased proteinuria and alleviated F-actin stress fiber disruption [PMID:26439819, PMID:29619899]
SPE enhanced BBB scores, improved inclined plane angles, and reduced inflammatory cytokines (TNF-α, IL-1β, IL-6, IL-17, IL-18) [PMID:41241801]
Extracts showed anti-hypoxic effects, including prolonged survival time in acute hypoxic preconditioning [PMID:31875579, PMID:32239860, PMID:32476549]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 39096544 (2024) — Przewaquinone A inhibits Angiotensin II-induced endothelial diastolic dysfunction activation of AMPK. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 2.PMID: 40311593 (2025) — Przewaquinone A, as a natural STAT3 inhibitor, suppresses the growth of melanoma cells and induces autophagy. · Phytomedicine : international journal of phytotherapy and phytopharmacology
- 3.PMID: 29191008 (2018) — Biomimetic Synthesis of Isorosmanol and Przewalskin A. · The Journal of organic chemistry
- 4.PMID: 34834049 (2021) — Regioisomers Salviprolin A and B, Unprecedented Rosmarinic Acid Conjugated Dinorditerpenoids from Salvia przewalskii Maxim. · Molecules (Basel, Switzerland)
- 5.PMID: 39195537