PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Oral administration of 3g of shallot per day (approx. 1.5 bulbs) as an adjuvant to cetirizine was studied for therapeutic effects [PMID:31421664]
Systematic review suggests shallot can be used as adjuvant therapy for these non-communicable diseases [PMID:35983491]
Topical application of shallot plant-derived nanovesicle hydrogels led to complete recovery of normal skin phenotype in murine models [PMID:40487455]
Aqueous extracts showed anti-growth activity in vitro against Jurkat and K562 tumor cell lines [PMID:22291731] and anti-carcinogenic properties against breast cancer in silico and in vitro [PMID:36331692]
Ethyl acetate fraction and essential oil demonstrated potent inhibitory activity against alpha-amylase, DPP-4, and PTP-1B in vitro [PMID:40820276]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 35983491 (2022) — Therapeutic Uses and Pharmacological Properties of Shallot (Allium ascalonicum): A Systematic Review. · Frontiers in nutrition
- 2.PMID: 35684272 (2022) — Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium ascalonicum L.) Extract. · Plants (Basel, Switzerland)
- 3.PMID: 31421664 (2022) — Antiallergic activities of shallot (Allium ascalonicum L.) and its therapeutic effects in allergic rhinitis. · Asian Pacific journal of allergy and immunology
- 4.PMID: 22291731 (2011) — Anticancer and anti-inflammatory activities of shallot (Allium ascalonicum) extract. · Archives of medical science : AMS
- 5.PMID: 12236699 (2002)