PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A saponin fraction (spartitrioside) from flowers showed potent anti-ulcerogenic effects in rat models by inhibiting gastric secretion volume and acidity [PMID:10837986]
Flower extracts demonstrated peripheral and central analgesic activity and a specific hexane extract fraction showed anti-inflammatory activity in rat models [PMID:17004903]
Treatment in adult rabbits and rats resulted in a significant decrease in fertility via reduction of the acrosomal protease system; the effect was reversible [PMID:8081803]
Aromatic water showed cytotoxic activity against several human cancer cell lines (melanoma, leukemia, breast cancer, and colon adenocarcinoma) without affecting normal keratinocytes [PMID:22428268]. Flower extracts inhibited growth and melanogenesis in B16-F10 murine melanoma cells by inducing senescence [PMID:30097108].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 24582126 (2014) — [Spartium junceum (Spanish broom) poisoning]. · Anales de pediatria (Barcelona, Spain : 2003)
- 2.PMID: 27931851 (2017) — Spanish Broom (Spartium junceum L.) fibers impregnated with vancomycin-loaded chitosan nanoparticles as new antibacterial wound dressing: Preparation, characterization and antibacterial activity. · European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
- 3.PMID: 11849323 (2002) — Bradyrhizobium sp. nodulating the Mediterranean shrub Spanish broom (Spartium junceum L.). · Journal of applied microbiology
- 4.PMID: 31955560 (2019) — Spartium junceum L. poisoning in small ruminants. · Veterinaria italiana
- 5.PMID: 33860374