PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
A proprietary blend of S. indicus flower head and Mangifera indica stem bark extracts (650 mg/day) was evaluated for ergogenic potential in young male volunteers [PMID:36794013].
A study on a formulation (Meratrim) containing S. indicus flower heads extract and Garcinia mangostana fruit revealed longer-term evidence for appetite suppression [PMID:31126562].
Methanolic and acetone extracts of flowers protected mice against PTZ and Picrotoxin induced convulsions, though not MES induced convulsions [PMID:30638715].
Methanol extract of the whole plant significantly decreased plasma glucose and serum triglyceride levels and stimulated glucose uptake in dexamethasone-induced insulin resistant mice [PMID:20738176].
A combination of S. indicus and Garcinia mangostana (Meratrim 450 mg/kg) significantly reduced body weight and fat mass in high-fat diet obese mice [PMID:39335940].
Evidence summary
PubMed sources
- 1.PMID: 24347924 (2013) — Review on Sphaeranthus indicus Linn. (Koṭṭaikkarantai). · Pharmacognosy reviews
- 2.PMID: 21455454 (2010) — Sphaeranthus indicus Linn.: A phytopharmacological review. · International journal of Ayurveda research
- 3.PMID: 28412842 (2017) — Four new Sesquiterpenoids from Sphaeranthus indicus. · Natural product research
- 4.PMID: 29618441 (2018) — Phytochemical screening and antibacterial potential of Artemisia absinthium L., Swertia chirayita and Sphaeranthus indicus. · Pakistan journal of pharmaceutical sciences
- 5.PMID: 30638715 (2019) — Anticonvulsant effect of Sphaeranthus flower extracts in mice.