PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 29 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Significant decrease in total cholesterol [PMID:37864474].
Supplementation decreased systolic blood pressure [PMID:37189189] and improved cardiometabolic risk factors [PMID:34334274].
Meta-analysis showed no significant effect on fasting blood glucose or HbA1c [PMID:34365008], though other studies suggest potential anti-diabetic properties [PMID:32816615].
3g/day supplementation significantly reduced appetite scores, serum leptin, NPY, insulin, and HOMA-IR [PMID:36753796].
Methanol extracts of Rhus glabra yielded antibacterial compounds including methyl gallate and 4-methoxy-3,5-dihydroxybenzoic acid [PMID:8072309].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 38925778 (2024) — Plant Dermatitis. · Emergency medicine clinics of North America
- 2.PMID: 32491789 (2026) — Rhus (Toxicodendron) dermatitis. · Primary care
- 3.PMID: 36638373 (2022) — Botanical Briefs: Toxicodendron Dermatitis. · Cutis
- 4.PMID: 28764017 (2017) — Chemical composition and biological activity of staghorn sumac (Rhus typhina). · Food chemistry
- 5.PMID: 32816615 (2021) — Could Sumac Be Effective on COVID-19 Treatment? · Journal of medicinal food
- 6.