PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Aqueous seed extract inhibited PDE-5, arginase, AChE, and ACE in isolated rat corpus cavernosum [PMID:31502274]
Supplemented diets (3% and 6%) decreased plasma and PMF lipid peroxidation in rats [PMID:17651070]
Unprocessed leaf extracts inhibited α-amylase and α-glucosidase activities in vitro [PMID:23570004]
Leaf extracts (5 mg or 10 mg/0.5 mL) significantly decreased serum ALP, GOT, and GPT in garlic-induced oxidative stress rat models [PMID:16379574]
Seed extracts protected against busulfan-induced and atrazine-induced testicular damage in mice and rats [PMID:31469002, PMID:32538183]
Hydroethanolic leaf extract (25-800 mg/kg) significantly increased the onset and reduced the duration of convulsions in mouse models [PMID:24044490]
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 36381540 (2022) — The Complete Genome Sequence of Telfairia occidentalis, the African Fluted Pumpkin. · Biodiversity genomes
- 2.PMID: 31502274 (2019) — Fluted pumpkin (Telfairia occidentalis) seed modulates some markers of erectile function in isolated rat's corpus cavernosum: Influence of polyphenol and amino acid constituents. · Journal of food biochemistry
- 3.PMID: 17651070 (2007) — Hypolipidemic effect of Telfairia occidentalis (fluted pumpkin) in rats fed a cholesterol-rich diet. · Journal of medicinal food
- 4.PMID: 30258790 (2018) — Spermatogenic and spermatotoxic effects of Telfairia occidentalis (Ugu) aqueous leaves extract in adult male Wistar rats (Rattus novergicus). · Toxicology reports
- 5.PMID: 23570004