PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 29 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Ethanolic extract of C. heyneana rhizome demonstrated anti-aging activity in rat skin by affecting epidermal thickness, sunburn cells, fibroblasts, and collagen fiber spacing [PMID:32219759, PMID:30008394].
Essential oil (CHEO) exhibited antibacterial activity against E. coli (MIC 3.9 µg/mL), Salmonella typhi, Shigella sonnei, and Bacillus cereus, showing a synergistic effect when combined with tetracycline [PMID:37218156].
Constituents 4-6 (oxycurcumenol epoxide, curcumenol, and isocurcumenol) demonstrated moderate inhibition against T-acute lymphoblastic leukaemia cells [PMID:20461629].
Ethanol extract and ethyl acetate fraction of the rhizome showed immunomodulatory potential in mice models, affecting phagocytosis index and leukocyte counts [PMID:37153401].
Drug interactions
Evidence summary
PubMed sources
- 1.PMID: 37765107 (2023) — Anti-Aging Potential of Plants of the Anak Dalam Tribe, Jambi, Indonesia. · Pharmaceuticals (Basel, Switzerland)
- 2.PMID: 20461629 (2010) — Bioactive sesquiterpenes from Curcuma ochrorhiza and Curcuma heyneana. · Natural product research
- 3.PMID: 30008394 (2018) — Anti-aging properties of Curcuma heyneana Valeton & Zipj: A scientific approach to its use in Javanese tradition. · Journal of ethnopharmacology
- 4.PMID: 37153401 (2023) — Immunomodulatory effect from ethanol extract and ethyl acetate fraction of Curcuma heyneana Valeton and Zijp: Transient receptor vanilloid protein approach. · Heliyon
- 5.PMID: 37218156 (2024) — Antibacterial, bacteriolytic, and antibiofilm activities of the essential oil of temu giring (Curcuma heyneana Val.) against foodborne pathogens.