PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 21 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Avicins D and G exhibit potent cytotoxicity and induce apoptosis in human T-cell leukemia (Jurkat cells) and breast cancer cell lines [PMID:12828461, PMID:11454696]. In murine models, avicins reduced the number of papillomas by 70% and decreased H-ras mutations in skin carcinogenesis [PMID:11572997].
A mixture of avicins (F094) enhanced the skin permeability of local anesthetics (lidocaine-HCl, prilocaine-HCl, and bupivacaine-HCL) by 2- to 5-fold in porcine skin [PMID:25786727].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 38051014 (2024) — Bringing back a forgotten legume-Sensory profiles of Australian native wattleseeds reveal potential for novel food applications. · Journal of food science
- 2.PMID: 25212304 (2011) — Characterisation of phenolic components present in raw and roasted wattle (Acacia victoriae Bentham) seeds. · Food chemistry
- 3.PMID: 31680210 (2019) — Chemical Composition and Anti-Nutritional Profiling of Wattle (Acacia cyclops, Acacia microbotrya and Acacia victoriae) Seed Originating from Western Australia. · Plant foods for human nutrition (Dordrecht, Netherlands)
- 4.PMID: 29986447 (2018) — Vitamin D Content of Australian Native Food Plants and Australian-Grown Edible Seaweed. · Nutrients
- 5.PMID: 17559228