PubMed-compiled information sheet
This sheet was compiled from PubMed (NIH) abstracts using AI assistance. Every factual claim is cited to a real PubMed article (see the source list). It has not yet been human-reviewed — confirm with a healthcare provider before use.
Compiled from 30 PubMed articles · model: gemma4:31b
Summary
Background
Traditional uses
Active compounds
Mechanism of action
Clinical evidence
Methanolic flower crude extract decreased lipopolysaccharide-induced interleukin-6 cytokine production in murine macrophages [PMID:40711949].
Essential oil showed antibacterial, antimycotic, and anti-inflammatory activities, performing superior to hydrocortisone in combination with vitamin B6 for anti-inflammatory activity [PMID:20396753].
Leaf and inflorescence essential oils inhibited the growth of six tested microorganisms at concentrations of 0.156-0.625 μL/mL [PMID:39325328].
Dry extract from hydrodistilled residue (MFDE) dose-dependently inhibited paw edema in rats [PMID:33995001].
Safety & adverse effects
Evidence summary
PubMed sources
- 1.PMID: 29744941 (2018) — Carvacrol and human health: A comprehensive review. · Phytotherapy research : PTR
- 2.PMID: 33806521 (2021) — The Volatile Phytochemistry of Monarda Species Growing in South Alabama. · Plants (Basel, Switzerland)
- 3.PMID: 33105614 (2020) — Essential Oils from Monarda fistulosa: Chemical Composition and Activation of Transient Receptor Potential A1 (TRPA1) Channels. · Molecules (Basel, Switzerland)
- 4.PMID: 40711949 (2025) — Monarda Fistulosa Flower Extract Decreases Interleukin-6 Production by Lipopolysaccharide-Stimulated RAW 264.7 Murine Macrophages. · Journal of medicinal food
- 5.PMID: 35792130 (2023) — Carvacrol as a Prospective Regulator of Cancer Targets/Signalling Pathways.